Acute Dialysis Quality Initiative.
نویسندگان
چکیده
Although renal replacement therapy (RRT) is the mainstay of supportive care in patients with severe acute renal failure (ARF), performance of this life-sustaining treatment can have untoward effects that contribute to the prolongation of renal failure or impede the ultimate recovery of renal function. Renal biopsies in patients with prolonged ARF managed using hemodialysis demonstrated regions of fresh tubular necrosis days to weeks after the initial inciting insult [1,2]. Both dialysis-associated hypotension and the activation of cellular and humoral mediators by exposure to the extracorporeal circuit have been proposed mechanisms of this ongoing parenchymal injury [2.]. Access catheter-associated complications, metabolic, and electrolyte disturbances related to the performance of RRT may also impact on outcomes in patients with ARF.
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عنوان ژورنال:
- Blood purification
دوره 19 2 شماره
صفحات -
تاریخ انتشار 2001